Using Your Genome and Big Data to Manage Your Health
Tuesday, November 28, 2017
Anita Tuvin Schlechter Auditorium, 7 p.m.
New technologies that determine DNA sequencing means we can now profile people over time to better predict and diagnose disease. Snyder will share his work in these new technologies and the power they hold to transform how we manage human health. A book sale and signing will follow the presentation.
This event is sponsored by the Clarke Forum for Contemporary Issues and co-sponsored by the Department of Biology and the Health Studies Program. It is also part of the Clarke Forum’s semester theme, Big Data.
Michael Snyder is the Stanford Ascherman Professor and chair of genetics and the director of the Center of Genomics and Personalized Medicine at Stanford University. Snyder received his Ph.D. training at the California Institute of Technology and carried out postdoctoral training at Stanford University. He is a leader in the field of functional genomics and proteomics, and one of the major participants of the ENCODE project. His laboratory study was the first to perform a large-scale functional genomics project in any organism, and has developed many technologies in genomics and proteomics. These including the development of proteome chips, high resolution tiling arrays for the entire human genome, methods for global mapping of transcription factor binding sites (ChIP-chip now replaced by ChIP-seq), paired end sequencing for mapping of structural variation in eukaryotes, de novo genome sequencing of genomes using high throughput technologies and RNA-Seq. These technologies have been used for characterizing genomes, proteomes and regulatory networks. Seminal findings from the Snyder laboratory include the discovery that much more of the human genome is transcribed and contains regulatory information than was previously appreciated, and a high diversity of transcription factor binding occurs both between and within species. He has also combined different state-of–the-art “omics” technologies to perform the first longitudinal detailed integrative personal omics profile (iPOP) of person and used this to assess disease risk and monitor disease states for personalized medicine. He is a cofounder of several biotechnology companies, including Protometrix (now part of Life Technologies), Affomix (now part of Illumina), Excelix, and Personalis, and he presently serves on the board of a number of companies.
The Clarke Forum’s Semester Theme & Faculty Seminar
Each semester the Clarke Forum devotes a major portion of its resources to programs organized around a semester theme that is also the basis for a faculty seminar. All members of the faculty are invited to propose topics for themes/faculty seminars. Past themes/faculty seminars have included Sexuality and Societies, Living in a World of Limits, The Meanings of Race, Water, Language, War at Home, Inequality and Mass Incarceration in the United States, and Disability. The theme/faculty seminar for the fall 2016 semester is Food. If you are interested in proposing a Clarke Forum theme/faculty seminar, please visit Proposing a Clarke Forum Theme/Faculty Seminar.
The Clarke Forum’s Leadership Theme
LEADERSHIP IN AN AGE OF UNCERTAINTY
The Clarke Forum for Contemporary Issues has established a series of programmatic events dedicated to the theme of leadership in an age of uncertainty. This new initiative is grounded on the reality that today’s generation of Dickinson students confronts a large number of intractable political, economic, and social problems: terrorism and the proliferation of weapons of mass destruction, environmental pollution, global warming, a sustainable energy policy, the ongoing financial crisis, the federal deficit, the amount of public and private debt, the health care crisis, along with issues regarding race, ethnicity, gender, and sexual orientation, as well as technology and privacy. These issues and problems directly or indirectly pose challenges to the College and the local community that may in time require fundamental changes in institutions, values, and practices across the public, private, and non-profit sectors of American society. How Dickinsonians respond to these challenges presents us with an opportunity for reflection on the meaning of leadership in the contemporary world. This series is partially supported by a fund created by Betty R. ’58 and Dan Churchill. One additional aspect of the Clarke Forum’s Leadership Theme is a series of interviews with our guest speakers. They address how, in their own experience, different variables like ethics, passion, risk/failure, play in terms of leadership.